Survival of Salmonella serovar Typhimurium inside porcine monocytes is associated with complement binding and suppression of the production of reactive oxygen species

ORAL PRESENTATIONS a mix survived differently in individual animals and in general, the culture combination resulted in good survival and persistence, as previously observed by Pedersen et al. (1992). Many studies have reported reductions in intestinal coliform and Enterobacteriaceae due to probiotic administration; however, some have seen no effects (Simon et al., 2003). In the present study most of the cultures resulted in reductions in faecal Enterobacteriaceae; in fact, reductions of up to 98 % were observed. However, except for day 15, these reductions were not statistically significant, probably due to the variation in counts between individual animals, a common observation in probiotic animal trials. This inconsistency may be explained by individual variations in response to probiotics due to the complexity of the intestine (Simon et al., 2003). Future experiments using larger treatment groups and deliberate Salmonella infection should provide further information on the pathogen-lowering ability of these cultures.